Bmi1-IRES-CreERT2
品系全名
C57BL/6Smoc-Bmi1em1(IRES-CreERT2)Smoc
目录号
NM-KI-200095
品系状态
精子冻存
基因信息
基因名
Bmi1
品系描述
将IRES-CreERT2插入到小鼠Bmi1基因终止密码子处。
验证数据
Fig 1. Cre-mediated recombination in Colon of Bmi1Cre/+; Rosa26tdTomato/+ mice .
Fig 2. Cre-mediated recombination in intestine of Bmi1Cre/+; Rosa26tdTomato/+ mice .
Fig 3. Detection of tdTomato(red) in various tissues of Bmi1Cre/+;Rosa26tdTomato/+ mice. Expression tissues include: choroid plexus, cornea, heart, lung, liver, stomach, salivary glands, brown fat, kidney, pancreas, small and large intestine, testis, thymus, adrenal gland. A few cells expressed in brain, spinal cord, muscle. (For more detailed information please contact our technical advisor.)
你也可能感兴趣
Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
查看