hF12
品系全名
C57BL/6Smoc-F12tm1(hF12)/Smoc
目录号
NM-HU-210017
品系状态
活体
基因信息
基因名
F12
品系描述
通过同源重组，将小鼠F12基因进行人源化修饰。
应用领域：药物筛选
*使用本品系发表的文献需注明: hF12 mice (Cat. NO. NM-HU-210017) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig1. Detection of F12 expression in liver by RT-PCR.
Wild type: only one band at 318 bp with primers F1/R1(mF12);
Homozygous: only one band at 274 bp with primers F2/R2(hF12);
Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig.2 Detection of human F12 (A) and mouse F12 (B) expression in serum by ELISA (male, 8-11wks, n=2).
Abbr. HO, homozygous; WT, wild type.
Fig.3 Detection of hF12 expression in serum by ELISA (male, n=3).
Abbr. HO, homozygous; WT, wild type.
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