hIL11/hIL11RA
品系全名
C57BL/6Smoc-Il11em1(hIL11)Il11ra1tm1(hIL11RA)/Smoc
目录号
NM-HU-210372
品系状态
胚胎冻存
基因信息
基因名
Tnfrsf4
基因名
Il11ra1
品系描述
通过hIL11(NM-HU-204981)和hIL11RA (NM-HU-204982)小鼠交配获得。
应用领域：药物筛选；免疫治疗
*使用本品系发表的文献需注明: hIL11/hIL11RA mice (Cat. NO. NM-HU-210372) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig1. Detection of hIL11 expression in lung homogenate by ELISA. Abbr. HO, homozygous; WT, wild type. Note. hIL11/hIL11RA and C57BL/6 mice were injected with LPS.
Fig2. Detection of hIL11RA expression in Kidney in C57BL/6 and HO/HO hIL11/hIL11RA knockin mice by IHC. Abbr. HO/HO, homozygous; WT, wild type. Note. The anti-human IL11RA Antibody cross-reacted with mouse IL11RA and humanized IL11RA.
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