Pbsn-2A-CreERT2

品系全名

C57BL/6Smoc-Pbsnem1(V5-2A-CreERT2-WPRE-polyA)Smoc

目录号

NM-KI-200190

品系状态

精子冻存

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基因信息

基因名
Pbsn

基因曾用名

PB; Prbs

NCBI ID

54192

MGI ID

1860484

Ensembl ID

ENSMUSG00000000003

Pubmed

Pbsn

人类同源基因

PBSN

品系描述

将V5-2A-CreERT2-WPRE-polyA共表达结构插入到小鼠Pbsn基因终止密码子处。
应用领域：Cre工具鼠，前列腺上皮细胞

验证数据

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Fig1. Expression Pattern of Tomato in PbsnCreERT2/+;Rosa26tdTomato/+ mice.

CreERT2-mediated recombination in prostate epithelial cells of PbsnCreERT2/+ ; Rosa26tdTomato/+ mice. This strain represents an effective tool for generating prostate specific-targeted mutants.

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Fig2. Cre mediated recombination in prostate of PbsnCreERT2/+;Rosa26tdTomato/+ mouse. 

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Fig3. Detection of tdTomato(red) in various tissues of PbsnCreERT2/+;Rosa26tdTomato/+ mouse. Expression tissues include: prostate, salivary gland. A few cells expressed in adrenal gland, pancreas, testis, muscle and thymus. Tissues that unexpressed include brain, spinal cord, eyeball, heart, lung, liver, stomach, brown fat, kidney, colon, small intestine, spleen, and skin. (9-week old, male) (For more detailed information please contact our technical advisor.)

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