Zbtb46-2A-CreERT2
品系全名
C57BL/6Smoc-Zbtb46em1(2A-CreERT2-WPRE-pA)Smoc
目录号
NM-KI-18021
品系状态
胚胎冻存
基因信息
基因名
Zbtb46
品系描述
验证数据
Fig 1. Cre-mediated recombination in spleen of Zbtb46CreERT2/+; Rosa26tdTomato/+ mice.
Fig 2. Detection of tdTomato (red) in various tissues of Zbtb46CreERT2/+; Rosa26tdTomato/+. Expression tissues include: liver, salivary gland, pituitary gland, adrenal gland, kidney, pancreas, spleen, testis, thymus. A few cells expressed in cerebellum, spinal cord, heart, brown fat, small intestine, colon, muscle, skin. (6.5-8 weeks old, male) (For more detailed information please contact our technical advisor.)
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Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
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