Flt3-2A-CreERT2
品系全名
C57BL/6Smoc-Flt3em1(2A-CreERT2)Smoc
目录号
NM-KI-231796
品系状态
活体
基因信息
基因名
Flt3
品系描述
验证数据
Fig1. Cre mediated recombination in bone marrow of Flt3CreERT2/+;Rosa26tdTomato/+ mouse.
Fig2. Detection of tdTomato(red) in various tissues of Flt3CreERT2/+;Rosa26tdTomato/+ mouse. Expression tissues include: lung, bone marrow, kidney, spleen and muscle. A few cells expressed in brain, liver, stomach, salivary gland, brown fat, adrenal gland, colon, testis, skin, thymus. Tissues that unexpressed include spinal cord, retina, heart, pancreas, small intestine and pituitary gland. (49-days old, male) (For more detailed information please contact our technical advisor.)
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Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
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