Foxp1-2A-Cre
品系全名
C57BL/6Smoc-Foxp1em(2A-Cre)Smoc
目录号
NM-KI-220118
品系状态
精子冻存
基因信息
基因名
Foxp1
品系描述
验证数据
Fig1. Cre mediated recombination in retina of Foxp1Cre/+;Rosa26tdTomato/+ mouse.
(GCL, ganglion cell layer; INL, inner nuclear layer; ONL, outer nuclear layer; RPE, retinal pigment epithelium; CH, choroid)
Fig2. Detection of tdTomato(red) in various tissues of Foxp1Cre/+;Rosa26tdTomato/+ mouse. Expression tissues include: retina, heart, lung, liver, stomach, salivary gland, spinal cord, adrenal gland, kidney, pancreas, colon, small intestine, spleen, testis and epididymis, muscle, skin and thymus. A few cells expressed in brain, brown fat. (61-day old, male) (For more detailed information please contact our technical advisor.)
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Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
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