hIL10
品系全名
C57BL/6Smoc-Il10tm4(hIL10)/Smoc
目录号
NM-HU-2000063
品系状态
胚胎冻存
基因信息
基因名
Il10
品系描述
通过同源重组，将小鼠Il10基因进行人源化修饰。
应用领域：细胞因子人源化模型；药物筛选
*使用本品系发表的文献需注明: hIL10 mice (Cat. NO. NM-HU-2000063) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig1. Detection of IL10 expression in bladder by RT-PCR.
Wild type: only one band at 362 bp with primers F1/R1(mIl10);
Homozygous: only one band at 196 bp with primers F2/R2(hIL10).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig2. Detection of human and mouse IL10 expression in serum by ELISA (n=2).
Abbr. HO, homozygous; WT, wild type.
Note. hIL10 and C57BL/6 mice were i.p. injected with LPS for 2h.
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