hIL1RL1
品系全名
C57BL/6Smoc-Il1rl1tm4(hIL1RL1)/Smoc
目录号
NM-HU-2000067
品系状态
精子冻存
基因信息
基因名
Il1rl1
品系描述
通过同源重组,将小鼠Il1rl1基因进行人源化修饰。
验证数据
Fig1. Detection of IL1RL1 expression in large intestine by RT-PCR in hIL1RL1 mice.
Wild type: only one band at 296 bp with primers F1/R1(mIl1rl1);
Homoygous: only one band at 367 bp with primers F2/R2(hIL1RL1);
Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig2. Expression of hIL1RL1 on CD4+ T cells in spleen in hIL1RL1/hIL4/hIL4R mice (NM-HU-232112), which were generated by crossing hIL4/hIL4R (NM-HU-2000106) with hIL1RL1 (NM-HU-2000067).
Fig3. Expression of hIL1RL1 on mast cells in bone marrow in hIL1RL1/hIL4/hIL4R mice (NM-HU-232112), which were generated by crossing hIL4/hIL4R (NM-HU-2000106) with hIL1RL1 (NM-HU-2000067).
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