hHER3(2)
品系全名
C57BL/6Smoc-Erbb3tm1(hERBB3)Smoc
目录号
NM-HU-225068
品系状态
活体
基因信息
基因名
Erbb3
品系描述
利用同源重组，将小鼠Erbb3基因进行人源化修饰。
*使用本品系发表的文献需注明: hHER3(2) mice (Cat. NO. NM-HU-225068) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig.1 Detection of ERBB3 expression in colon by RT-PCR.
Wild type: only one band at 343 bp with primers F1/R1(mErbb3);
Homozygous: only one band at 305 bp with primers F2/R2(hERBB3).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of human hHER3 expression in hHER3(2) knockin mice by WB.
Abbr. M, marker; WT, wild type; HO, homozygous; PC, positive control, MC38-hHER3 cells.
Note. The anti-human hHER3 antibody cross-reacted with mouse hHER3 and humanized hHER3.
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