Tek-Cre(SD)
品系全名
SD-Tekem1(Cre)Smoc
目录号
NR-KI-210133
品系状态
活体
基因信息
品系描述
验证数据
Fig 1. Cre-mediated recombination in aorta of TekCre/+; Rosa26mTmG+ rat.
Fig 2. Detection of tdTomato (red) and GFP (green) in various tissues of TekCre/+; Rosa26mTmG+ rat. Expression tissues include: brain, eyeball, heart, lung, liver, salivary gland, brown fat, pituitary gland, aorta, kidney, spleen, pancreas, testis, skin, adrenal gland. A few cells expressed in spinal cord, stomach, colon, small intestine, muscle, thymus. (37-day old, male) (For more detailed information please contact our technical advisor.)
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Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
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