Pah-R261Q
品系全名
C57BL/6Smoc-Pahem(R261Q)Smoc
目录号
NM-KI-225102
品系状态
精子冻存
基因信息
基因名
Pah
品系描述
将小鼠Pah第261位R替换为Q，建立该Pah点突变小鼠模型。
*使用本品系发表的文献需注明: Pah-R261Q mice (Cat. NO. NM-KI-225102) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig1. Sequencing results of the Pah locus in the wild type and homozygous Pah-R261Q mice.
Fig2. 5-months-old hom Pah-R261Q mice were no different from their heterozygote counterparts and WT C57BL/6 mice in length and pigmentation.
Fig3. Detection of PAH expression in kidney and liver in Pah-R261Q mice.
Fig4. Detection of blood serum concentrations of the metabolites in Pah-R261Q mice by LC-MS
Table1. Detection of blood serum concentrations of the metabolites in Pah-R261Q mice
你也可能感兴趣
Tamoxifen诱导Cre-ERT2小鼠 使用指南
Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。
查看
