pAlb-hLPA-Tg
品系全名
C57BL/6Smoc-Tg(pAlb-hLPA)1Smoc
目录号
NM-TG-225001
品系状态
活体
基因信息
基因名
品系描述
通过随机转基因方式，将pAlb-hLPA整合到小鼠染色体。
应用领域：核酸药物人源化
*使用本品系发表的文献需注明: pAlb-hLPA-Tg mice (Cat. NO. NM-TG-225001) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig1. Detection of hLPA expression in serum by ELISA (n=15).
Abbr. WT, wild type.
Fig2. Detection of serum LPa protein level (A) and liver mRNA remaining (B) after single dose of positive control compound (n=2/group). (Data from a collaborator)
Fig3. Detection of serum LPa protein level (A) and liver mRNA remaining (B) after single dose of test compounds (n=4/group). (Data from a collaborator)
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