Fas-KO(BALB/c)

MGI:3665495
注：该品系需与Ccr2-KO(NM-KO-190018)交配才可能获得预期表型

de Lema GP, Maier H, Franz TJ, Escribese M, Chilla S, Segerer S, Camarasa N, Schmid H, Banas B, Kalaydjiev S, Busch DH, Pfeffer K, Mampaso F, Schlondorff D, Luckow B, Chemokine receptor Ccr2 deficiency reduces renal disease and prolongs survival in MRL/lpr lupus-prone mice. J Am Soc Nephrol. 2005 Dec;16(12):3592-601

MGI:3800222
注：该品系需与Tnfrsf9-KO(2)(NM-KO-210216)交配才可能获得预期表型

Ohta A, Sekimoto M, Sato M, Koda T, Nishimura S, Iwakura Y, Sekikawa K, Nishimura T, Indispensable role for TNF-alpha and IFN-gamma at the effector phase of liver injury mediated by Th1 cells specific to hepatitis B virus surface antigen. J Immunol. 2000 Jul 15;165(2):956-61

MGI:5478500
注：该品系需与Tlr9-KO(NM-KO-190168)交配才可能获得预期表型

Christensen SR, Shupe J, Nickerson K, Kashgarian M, Flavell RA, Shlomchik MJ, Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. Immunity. 2006 Sep;25(3):417-28

MGI:2450098

Adachi M, SuematsuS, Suda T, Watanabe D, FukuyamaH, Ogasawara J, Tanaka T, Yoshida N, Nagata S, Enhanced and accelerated lymphoproliferation in Fas-null mice. Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):2131-6