hAXL
品系全名
C57BL/6Smoc-Axltm1(hAXL)Smoc
目录号
NM-HU-215067
品系状态
胚胎冻存
基因信息
基因名
AXL
品系描述
利用同源重组，将小鼠Axl基因进行人源化修饰。
*使用本品系发表的文献需注明: hAXL mice (Cat. NO. NM-HU-215067) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig1. Detection of AXL expression in lung and spleen by RT-PCR.
Wild type: only one band at 202 bp with primers F1/R1(mAxl); Homozygous: only one band at 249 bp with primers F2/R2(hAXL). Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig2. Detection of human AXL expression in liver in hAXL knockin mice by WB.
Livers were collected from wild-type mice (+/+) and homozygous hAXL mice (HO/HO), and analyzed by western blot with anti-AXL antibody. Abbr. HO/HO, homozygous; +/+, wild type.
你也可能感兴趣
Tamoxifen诱导Cre-ERT2小鼠 使用指南
Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。
查看
