hIL15-Tg(M-NSG)
品系全名
NOD.Cg-PrkdcscidIl2rgem1Tg(hIL15)Smoc
目录号
NM-KI-210141
品系状态
活体
基因信息
基因名
Il15
品系描述
利用转基因技术将人源IL15基因表达框整合到小鼠基因组中，从而表达人源IL15。
*使用本品系发表的文献需注明: hIL15-Tg(M-NSG) mice (Cat. NO. NM-KI-210141) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig1. Human IL15 expression analysis in hIL15-Tg(N-NSG) mice by ELISA.
Fig2. Body weight of hIL15-Tg(M-NSG) post inoculation.
Fig3. Humanized immune reconstitution levels in hIL15-Tg(M-NSG) mice engrafted with human HSC.
Fig4. hIL15-Tg(M-NSG) mice engrafted with human HSCs exhibit high expression of functional proteins such as NKG2D, Granzyme B, and NKp46.
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