hFCRN(M-NSG)
品系全名
NOD.Cg-PrkdcscidIl2rgem1Fcgrtem2(FCGRT)Smoc
目录号
NM-NSG-020
品系状态
胚胎冻存
基因信息
基因名
Fcgrt
品系描述
该品系背景为M-NSG，其内源Fcgrt基因部分或全部替换为人源FCGRT。
应用领域：免疫治疗；肿瘤研究；药物筛选
*使用本品系发表的文献需注明: hFCRN(M-NSG) mice (Cat. NO. NM-NSG-020) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig.1 Detection of FCRN expression in kidney by RT-PCR.
Wild type: only one band at 181 bp with primers F1/R1(mFcgrt);
Heterozygous: one band at 181 bp with primers F1/R1(mFcgrt) and one band at 310 bp with primers F2/R2(hFCGRT).
Abbr. M, DNA marker; HE, heterozygous; WT, wild type.
Fig.2 Detection of human FCRN expression in hFCRN (M-NSG) mice by WB.
Abbr. M, marker; WT1, wild type, NOD-Scid; WT2, wild type, M-NSG; HE, heterozygous; PC, positive control, hFCRN (NM-HU-190070).
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