hCFTR
品系全名
C57BL/6Smoc-Cftrtm1(hCFTR)Smoc
目录号
NM-HU-225060
品系状态
活体
基因信息
基因名
Cftr
品系描述
利用同源重组，将小鼠Cftr基因进行人源化修饰。
*使用本品系发表的文献需注明: hCFTR mice (Cat. NO. NM-HU-225060) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig.1 Detection of CFTR expression in testis by RT-PCR.
Wild type: only one band at 209 bp with primers F1/R1(mCftr);
Homozygous: only one band at 227 bp with primers F2/R2(hCFTR).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of human CFTR expression in hCFTR knockin mice by WB.
Abbr. M, marker; WT, wild type; HO, Homozygous; PC, positive control, HepG2 cells.
Note. The anti-human CFTR antibody cross-reacted with mouse and humanized CFTR.
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