hTIGIT(BALB/c,2)
品系全名
BALB/cAnSmoc-Tigittm4(hTIGIT)Smoc
目录号
NM-HU-200245
品系状态
活体
基因信息
基因名
TIGIT
品系描述
通过同源重组，将小鼠基因Tigit进行人源化修饰。原hTIGIT(BALB/c)(NM-HU-2000043)小鼠模型因技术原因已下架。
*使用本品系发表的文献需注明: hTIGIT(BALB/c,2) mice (Cat. NO. NM-HU-200245) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig.1 Detection of TIGIT expression in large intestine by RT-PCR.
Wild type: only one band at 126 bp with primers F1/R1(mTigit);
Homozygous: only one band at 168 bp with primers F2/R2(hTIGIT).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of hTIGIT expression on splenocytes-derived activated T cells in hTIGIT KI mice.
Note. Splenocytes from BALB/c and HO hTIGIT mice were stimulated with ConA in vitro.
你也可能感兴趣
Tamoxifen诱导Cre-ERT2小鼠 使用指南
Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。
查看
