Foxg1-Cre
品系全名
C57BL/6Smoc-Foxg1em1(Cre-WPRE-polyA)Smoc
目录号
NM-KI-200156
品系状态
精子冻存
基因信息
基因名
品系描述
验证数据
Fig 1. Cre-mediated recombination in brain of Foxg1Cre/+; Rosa26tdTomato/+ mice.
Fig 2. Detection of tdTomato (red) in various tissues of Foxg1Cre/+; Rosa26tdTomato/+ mice. Expression tissues include: brain, retina, heart, lung, liver, stomach, salivary glands, brown fat, kidney, pancreas, small intestine, large intestine, ovary, thymus, adrenal gland. A few cells expressed in spinal cord, spleen, muscle, skin. (9-week old, female) (For more detailed information please contact our technical advisor.)
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Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
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