Trdc-IRES-CreERT2
品系全名
C57BL/6Smoc-Trdcem1(IRES-CreERT2)Smoc
目录号
NM-KI-231464
品系状态
精子冻存
基因信息
基因名
品系描述
将IRES-CreERT2插入到小鼠Trdc基因终止密码子之后。
*使用本品系发表的文献需注明: Trdc-IRES-CreERT2 mice (Cat. NO. NM-KI-231464) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig1. CreERT2 mediated recombination in small intestine of TrdcCreERT2/+; Rosa26zsGreen/+ mouse.
Fig2. Detection of zsGreen(green) in various tissues of TrdcCreERT2/+; Rosa26zsGreen/+ mouse. Tissues expressing zsGreen: lung, liver, stomach, salivary gland, large intestine, small intestine, pancreas, reproduction, muscle, skin, adrenal gland, thymus. zsGreen is sporadically expressed in brain, eyeball, brown fat pituitary and spinal cord. (8-weeks old, female) (For more detailed information please contact our technical advisor.)
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Tamoxifen诱导Cre-ERT2小鼠 使用指南
Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。
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