Syn1-IRES-CreERT2

品系全名

C57BL/6Smoc-Syn1em1(IRES-CreERT2)Smoc

目录号

NM-KI-231789

品系状态

精子冻存

导出PDF

基因信息

基因名
Syn1

品系描述

将IRES-CreERT2插入到小鼠Syn1基因终止密码子处。

验证数据

image.png

Fig 1. Cre-mediated recombination in brain of Syn1CreERT2/+; Rosa26tdTomato/+ mice.

image.png

Fig 2. Cre-mediated recombination in brain of Syn1CreERT2/+; Rosa26tdTomato/+ mice.

image.png

Fig 3. Detection of tdTomato (red) in various tissues of Syn1CreERT2/+; Rosa26tdTomato/+ mice. Expression tissues include: brain, retina, islet, pituitary. A few cells expressed in spinal cord, heart, lung, liver, adrenal gland, kidney, small intestine, colon, muscle and thymus. Tissues that unexpressed include  stomach, salivary glands, brown fat, spleen, uterus, skin. Tamoxifen induction began at 35 days of age, with testing at 45 days. (45-day old, female) (For more detailed information please contact our technical advisor.) 


你也可能感兴趣

Tamoxifen诱导Cre-ERT2小鼠 使用指南

Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。

查看
【小鼠大学问】基因工程小鼠的命名规则

常见的基因工程小鼠可以分为两种命名方式,包括基因定点修饰的小鼠命名,比如:敲除、敲入、点突变等等,和随机转基因的小鼠命名。

查看