Cspg4-CreERT2-2A
品系全名
C57BL/6Smoc-Cspg4em(CreERT2-P2A)1Smoc
目录号
NM-KI-225033
品系状态
精子冻存
基因信息
基因名
Cspg4
品系描述
验证数据
Fig 1. Cre-mediated recombination in Cortex of Cspg4CreERT2/+; Rosa26tdTomato/+ mice.
Fig 2. Detection of tdTomato (red) in various tissues of Cspg4CreERT2/+; Rosa26tdTomato/+ mice. Expression tissues include: brain, spinal cord, cornea, lung, liver, brown fat, kidney, small intestine, colon, uterus, muscle and skin. A few cells expressed in heart, stomach, adrenal gland, pancreas, spleen, ovary and thymus. Tissues that unexpressed include salivary glands. (5-week old, female) (For more detailed information please contact our technical advisor.)
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Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
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