Sox10-2A-Cre
品系全名
C57BL/6Smoc-Sox10em(2A-Cre)Smoc
目录号
NM-KI-220066
品系状态
活体
基因信息
基因名
Sox10
品系描述
验证数据
Fig 1. Photographs of the back and abdomen of Sox10Cre/+; Rosa26tdTomato/+ mice.
Fig 2. Cre-mediated recombination in occipital skull of Sox10Cre/+; Rosa26tdTomato/+ mice.
Fig 3. Cre-mediated recombination in intestines of Sox10Cre/+; Rosa26tdTomato/+ mice.
Fig 4. Detection of tdTomato(red) in various tissues of Sox10Cre/+; Rosa26tdTomato/+ mice. Expression tissues include: brain, pituitary gland, eyeball, heart, lung, liver, stomach, salivary gland, kidney, pancreas, small intestine, colon, testis, epididymis, thymus and tongue. A few cells expressed in brown fat, adrenal gland, spleen, muscle, skin. (8-week old, male) (For more detailed information please contact our technical advisor.)
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Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
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