Muc2-2A-CreERT2-IRES-tdTomato

将2A-CreERT2-tdTomato-Wpre-pA插入到小鼠Muc2基因终止密码子处。

Fig 1. Active tdTomato expression was observed in the large intestine of Muc2^{CreERT2-IRES-tdTomato/+}  mouse. WT, wild type as control.

Fig 2. Active tdTomato expression was observed  in the small intestine of Muc2^{CreERT2-IRES-tdTomato/+} mouse. WT, wild type as control.

Fig 3. No obvious tdTomato signal was observed in the stomach of Muc2CreERT2-IRES-tdTomato/+ mouse. WT, wild type as control.

Fig 4. Active tdTomato signal was observed in the colon of Muc2CreERT2-IRES-tdTomato/+ mouse. WT, wild type as control.

Fig 5. Active tdTomato signal was observed in the cecum of Muc2CreERT2-IRES-tdTomato/+ mouse. WT, wild type as control.

Fig 6. TdTomato signal was observed in the small intestine of Muc2CreERT2-IRES-tdTomato/+ mouse.WT, wild type as control.

Fig 7. No obvious tdTomato signal was observed in the stomach of Muc2CreERT2-IRES-tdTomato/+ mouse. WT, wild type as control.

Slowed Intestinal Transit Induced by Less Mucus in Intestinal Goblet Cell Piezo1-Deficient Mice through Impaired Epithelial Homeostasis
来源杂志：MDPI