hCCL1
品系全名
C57BL/6Smoc-Ccl1em2(hCCL1)/Smoc
目录号
NM-HU-2000074
品系状态
胚胎冻存
基因信息
基因名
Ccl1
品系描述
通过同源重组，将小鼠Ccl1基因进行人源化修饰。
应用领域：免疫治疗；药物筛选
*使用本品系发表的文献需注明: hCCL1 mice (Cat. NO. NM-HU-2000074) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig.1 Detection of CCL1 expression in thymus by RT-PCR.
Wild type: only one band at 197 bp with primers F1/R1(mCcl1);
Homozygous: only one band at 194 bp with primers F2/R2(hCCL1).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of hCCL1 and mCCL1 expression in serum by ELISA (6-8wks, female, n=3).
Abbr. HO, homozygous; WT, wild type.
Note. hCCL1 and C57BL/6 mice were i.p. injected with con.A for 3h.
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