NVG-hIL15
品系全名
NOD.Cg-PrkdcscidIl2rgem1SmocIl15em1(hIL15)Smoc
目录号
GM-NVG-210001
品系状态
活体
基因信息
基因名
Il15
品系描述
通过同源重组,将小鼠Il15基因进行人源化修饰。
验证数据
Human IL15 expression analysis
Fig 1. Human IL15 expression analysis in homozygous NVG-hIL15 mice by ELISA.
Fig 2. Humanized immune reconstitution levels and body weight growth curves in huPBMC-NVG-hIL15 mice.
Fig 3. Humanized immune reconstitution levels and body weight growth curves in huPBNK-NVG-hIL15 mice.
Fig 4. Efficacy evaluation of CD20-targeting antibody using Raji huPBNK model.
Fig 5. Functional protein detection in NK cells in the presence of anti-hCD20 antibody drug using Raji huPBNK model.
Fig 6. ADCC efficacy research in vitro using huPBNK model.
Fig 7. Body weight growth curves in γδT-NVG-hIL15 mice.
Fig 8. Survial rates in γδT-NVG-hIL15 mice.
Fig 9. Humanized immune reconstitution levels in γδT-NVG-hIL15 mice.
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