hIL18BP

品系全名

C57BL/6Smoc-Il18bpem1(hIL18BP)Smoc

目录号

NM-HU-210039

品系状态

胚胎冻存

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基因信息

基因名
Il18bp

基因曾用名

MC54L; Igifbp; IL-18BP

NCBI ID

16068

MGI ID

1333800

Ensembl ID

ENSMUSG00000070427

Pubmed

Il18bp

人类同源基因

IL18BP

品系描述

通过同源重组，将小鼠Il18bp基因进行人源化修饰。
应用领域：免疫治疗；药物筛选

验证数据

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Fig1. Detection of IL18BP expression in thymus and liver by RT-PCR. Wild type: only one band at 354 bp with primers F1/R1(mIl18bp);Heterozygous: one band at 354 bp with primers F1/R1(mIl18bp) and one band at 220 bp with primers F2/R2(hIL18BP); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig2. Detection of IL18BP expression in thymus and liver by RT-PCR.  Wild type: only one band at 354 bp with primers F1/R1(mIl18bp); Homozygous: only one band at 220 bp with primers F2/R2(hIL18BP);  Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig3. Detection of hIL18BP expression in serum by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

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Fig4. Detection of mIL18BP expression in serum by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

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Fig5. Detection of hIL18BP expression in serum by ELISA (n=3). Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

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Fig6. Detection of mIL18BP expression in serum by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

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