hCCL4
品系全名
C57BL/6Smoc-Ccl4em1(hCCL4)/Smoc
目录号
NM-HU-210013
品系状态
胚胎冻存
基因信息
基因名
Ccl4
品系描述
通过同源重组，将小鼠Ccl4基因进行人源化修饰。
应用领域：药物筛选
*使用本品系发表的文献需注明: hCCL4 mice (Cat. NO. NM-HU-210013) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig1. Detection of CCL4 expression in small intestine, spleen and thymus by RT-PCR. Wild type: only one band at 242 bp with primers F1/R1(mCcl4); Homozygous: only one band at 144 bp with primers F2/R2(hCCL4); Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig 2. Detection of hCCL4 expression in plasma by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type. Note. hCCL4 and C57BL/6 mice were i.p. injected with LPS(20mg/kg) for 6h.
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