H11-pAlb-hBAFF

将pAlb-hBAFF-pA插入到小鼠H11位点。

Fig.1 Detection of hBAFF expression in serum by ELISA. 

Abbr.  WT, wild type; HE, heterozygous.

Fig.2 Detection of immune phenotype in WT C57BL/6 and HE H11-pAlb-hBAFF mice.

Fig.3 Detection of phenotype in Peripheral blood in WT C57BL/6 and HE H11-pAlb-hBAFF mice.

Fig.4 Detection of phenotype in Spleen in WT C57BL/6 and HE H11-pAlb-hBAFF mice.

Fig.5 Detection of phenotype in Lymph node in WT C57BL/6 and HE H11-pAlb-hBAFF mice.

Fig.6 Detection of phenotype in Bone marrow in WT C57BL/6 and HE H11-pAlb-hBAFF mice.

Fig.7 Body weight(A) and urine biochemistry analysis(B) of H11-pAlb-hBAFF mice at different time points. (Day 0 : 9 Weeks age)

Fig.8 Tissue weights and photos of H11-pAlb-hBAFF mice at different time points.

Fig.9 Detect the dsDNA levels in the blood of H11-pAlb-hBAFF mice at 11 weeks of age. (Kit information: Apha Diagnostic, 5120)

Fig.10 Expression characterization of mIgA (A), mIgE (B), mIgM (C) and mIgG (D) in HE H11-pAlb-hBAFF mice by ELISA.