hCXCR6
品系全名
C57BL/6Smoc-Cxcr6em(hCXCR6)Smoc
目录号
NM-HU-215001
品系状态
活体
基因信息
基因名
Cxcr6
品系描述
利用同源重组，将小鼠Cxcr6进行人源化修饰。
*使用本品系发表的文献需注明: hCXCR6 mice (Cat. NO. NM-HU-215001) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig1. Detection of CXCR6 expression in spleen by RT-PCR. Wild type: only one band at 423 bp with primers F1/R1(mCxcr6);Homozygous: only one band at 206 bp with primers F2/R2(hCXCR6); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig2. Detection of hCXCR6 expression on NKT cells in spleen in hCXCR6 KI mice.
Fig3. Detection of hCXCR6 expression on splenocyte-derived activated T cells in hCXCR6 KI mice.
Note. Splenocytes from C57BL/6 and homozygous hCXCR6 mice were stimulated with anti-mCD3 and anti-mCD28 in vitro.
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