hPVRL2
品系全名
C57BL/6Smoc-Nectin2tm1(hNECTIN2)/Smoc
目录号
NM-HU-2000084
品系状态
胚胎冻存
基因信息
基因名
Nectin2
品系描述
通过同源重组，将小鼠Nectin2基因进行人源化修饰。
应用领域：免疫治疗；药物筛选
*使用本品系发表的文献需注明: hPVRL2 mice (Cat. NO. NM-HU-2000084) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig1. Detection of PVRL2 expression in duodenum and large Intestine by RT-PCR.
Wild type: only one band at 342 bp with primers F1/R1 (mPvrl2);
Homozygous: only one band at 228 bp with primers F2/R2 (hPVRL2);
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig2. Detection of human PVRL2 expression in duodenum and large Intestine in hPVRL2 KI mice.
Fig3. Detection of hPVRL2 expression on marcophages and dendritic cells in hPVRL2 KI mice.
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